Essentials of Nuclear Medicine Imaging E-Book

Milton J. Guiberteau, Fred A. Mettler

Description

Essentials of Nuclear Medicine Imaging, by Drs. Fred A Mettler and Milton J Guiberteau, provides the practical and comprehensive guidance you need to master key nuclear imaging techniques. From physics, instrumentation, quality control, and legal requirements to hot topics such as sodium fluoride, radiopharmaceuticals, and recommended pediatric administered doses and guidelines, this sixth edition covers the fundamentals and recent developments in the practice of nuclear medicine.

• Get comprehensive coverage of key techniques such as PET/CT, cardiac-gated SPECT, and tumor-specific radionuclides, as well as Cerebrovascular System, Cardiovascular System, Conventional Neoplasm Imaging and Radioimmunotherapy, and Positron Emission Tomography Imaging.
• Reference practical clinical guidance at a glance from important "Pearls and Pitfalls" in each chapter and. helpful appendices including Injection Techniques, Pediatric Dosages, Non-radioactive Pharmaceuticals, and many more
• Assess your understanding with a section of Unknown Case Sets—expanded in this edition.
• Find information quickly and easily with a full-color format.

• Apply the latest best practices thanks to extensive updates of clinical guidelines that reflect recent changes in the practice of nuclear medicine, including the use of sodium fluoride (F-18 FDG for infections and Na F-18 for skeletal imaging), suggested radiopharmaceuticals for imaging various types of tumors, and imaging procedures and new classification schemes for pulmonary embolism.
• Effectively use PET/CT in imaging neoplasms with coverage of the most current indications.
• Manage radition safety concerns using quality control procedures for hybrid imaging equipment, patient and radiation safety checklists for I-131 therapy for hyperthyroidism and thyroid cancer, and recommended pediatric administered doses and guidelines.
• Get a clear view of the current state of imaging from high-quality images - 35% new to this edition.

Sujets

• Artículo científico
• Derecho de autor
• United States of America
• Chronic obstructive pulmonary disease
• Hodgkin's lymphoma
• SAFETY
• Cirrhosis
• Amnesia
• Iminodiacetic acid
• Myocardial infarction
• Photocopier
• Alzheimer's disease
• Emergency procedure
• Bronchitis
• Thyroid nodule
• Elective surgery
• Emphysema
• Pseudohermaphroditism
• Iodine-123
• Non-small cell lung carcinoma
• Pentetic acid
• Vitality
• Radioimmunotherapy
• Iodine-125
• Temporal lobe epilepsy
• Renovascular hypertension
• Isotopes of gallium
• Isotopes of strontium
• Isotopes of yttrium
• Isotopes of indium
• Isotopes of rhenium
• Xenon-133
• Iodine-131
• Technetium-99m generator
• Pregnancy
• Crystallization
• Neoplasm
• Collimator
• Medical record
• Urinary retention
• Radiopharmacology
• Human decontamination
• Fractionation
• Medical Center
• Melanoma
• Chronic kidney disease
• Acute kidney injury
• Stroke
• Renal function
• Genitourinary system
• Dilated cardiomyopathy
• Abdominal pain
• Sterility
• Ewing's sarcoma
• Physician assistant
• Glycemic index
• Tomography
• Pleural effusion
• Nuclear medicine
• Bronchiectasis
• Veteran
• Osteosarcoma
• Cholecystitis
• Single photon emission computed tomography
• Parathyroid gland
• Gallstone
• Heart failure
• Salivary gland
• Pulmonary embolism
• Radioactive decay
• Physical exercise
• Glove
• Human skeleton
• Chart
• Medical ultrasonography
• Atherosclerosis
• Sodium chloride
• Hypertension
• Non-Hodgkin lymphoma
• Respiratory system
• Angina pectoris
• Hypothyroidism
• Circulatory system
• Camera
• Pneumonia
• X-ray computed tomography
• Philadelphia
• Surgery
• Dementia
• Radionuclide
• Infection
• Thyroid
• Sinusitis
• Data storage device
• International System of Units
• Positron emission tomography
• Mechanics
• Magnetic resonance imaging
• Iodine
• Hyperthyroidism
• Epilepsy
• Chemotherapy
• Chemical element
• Colloid
• Antacid
• Adrenal gland
• Antibacterial
• Cyclophosphamide
• Technétium 99m
• Hypertension artérielle
• Paper
• Human
• Contamination
• États-Unis
• Water
• Neuraxis
• Perfusion
• Stérile
• Radio-Activity (album)
• Instruction
• Supination
• Release
• Hit-parade
• Electronic
• Service
• Acid
• Maladie infectieuse
• Philadelphie
• Thallium
• 3
• Isotope
• Copyright
• Photon
• Système international d'unités

Informations

• Publié par: Saunders
• Date de parution: 15 novembre 2011
• Nombre de lectures: 0
• EAN13: 9781455738175
• Langue: English
• Poids de l'ouvrage: 12 Mo

Extrait

Essentials of Nuclear Medicine Imaging
Sixth Edition

Fred A. Mettler, Jr., MD, MPH
Imaging Service, New Mexico Veteran's Affairs Heath Care System
Clinical and Emeritus Professor, University of New Mexico School of Medicine, Albuquerque, New Mexico

Milton J. Guiberteau, MD
Professor of Clinical Radiology and Nuclear Medicine, University of Texas Medical School at Houston
Academic Chief, Department of Medical Imaging, Director of Nuclear Medicine, St. Joseph Medical Center, Houston, Texas
Saunders
Front Matter

Essentials of Nuclear Medicine Imaging
6 th Edition
FRED A. METTLER, JR., MD, MPH
Imaging Service, New Mexico Veteran’s Affairs Heath Care System, Clinical and Emeritus Professor, University of New Mexico School of Medicine, Albuquerque, New Mexico
MILTON J. GUIBERTEAU, MD
Professor of Clinical Radiology and Nuclear Medicine, University of Texas Medical School at Houston, Academic Chief, Department of Medical Imaging, Director of Nuclear Medicine, St. Joseph Medical Center, Houston, Texas
Copyright

1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
ESSENTIALS OF NUCLEAR MEDICINE IMAGING, 6 th Edition ISBN: 978-1-4557-0104-9
Copyright © 2012, 2006, 1998, 1991, 1985, 1983 by Saunders, an imprint of Elsevier Inc.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notice
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment, and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the publisher nor the editors assume any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.
Library of Congress Cataloging-in-Publication Data
Mettler, Fred A., 1945-
Essentials of nuclear medicine imaging / Fred A. Mettler Jr., Milton
J. Guiberteau. -- 6th ed.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-1-4557-0104-9 (pbk. : alk. paper)
I. Guiberteau, Milton J. II. Title.
[DNLM: 1. Nuclear Medicine--methods. 2. Radionuclide Imaging. 3.
Radiopharmaceuticals. 4. Radiotherapy. WN 445]
616.07575--dc23 2011040394
Acquisitions Editor: Don Scholz
Developmental Editor: Lora Sickora
Publishing Services Manager: Anne Altepeter
Project Managers: Kiruthiga Kasthuri/Louise King
Marketing Manager: Tracie Pasker
Printed in China
Last digit is the print number:987654321
Dedication
To our parents, our families, and those who spend their time teaching residents
Preface
Six years have elapsed since publication of the fifth edition of Nuclear Medicine Imaging, and it has been 34 years since the first edition. In this sixth edition, we have made revisions that reflect changes in the current practice of nuclear medicine and molecular imaging, while maintaining our focus on the essential elements. We have also endeavored to retain the book’s prior extent and affordability. Since the previous edition, there has been continued change, not only in the patterns of use of existing nuclear medicine studies but also notably in the evolution of radiopharmaceuticals and instrumentation, such as the widespread use of hybrid imaging (especially PET/CT and SPECT/CT).
The progressive integration of traditional nuclear medicine techniques with those of diagnostic radiology, providing both anatomic and functional information on a single set of coregistered images, has added powerful tools to the diagnosis of disease and the assessment of treatment effectiveness. At the same time, it has increased the need for imagers to broaden their imaging skills. These considerations are addressed in this edition. Further, enhanced equipment automation has allowed information about quality control to be condensed and included in Chapters 1 and 2.
We have updated all chapters to include recent developments in instrumentation and radiopharmaceuticals. We have also limited content on less common and outmoded procedures, and removed outdated content. We have added new material on procedure guidelines (such as GI emptying studies and Na- 18 F bone scanning). The expanded use of PET has permitted material on PET and PET/CT imaging for CNS and cardiac applications to be relocated to those organ-specific chapters, and we have organized separate chapters on non-PET and PET neoplasm imaging. Information relative to the duties and expectations of an authorized user (AU) has been updated and clarified.
We have noted that residents supplement their clinical case experience with atlases and casebooks. There are more than 400 figures in this edition, and about 40% of the illustrations are entirely new. We have also included in the text, where appropriate, information on how to use radiation (dosing) wisely. At the end of the text, we have updated and revised the Unknown Case Sets in a more familiar and, hopefully, instructive format. Review of the sets will allow readers to assess their knowledge in a commonly employed format and to gain familiarity with commonly encountered nuclear imaging entities.

Fred A. Mettler, Jr.

Milton J. Guiberteau
Acknowledgments
We would like to recognize the many residents, technologists, and others who provided suggestions, as well as a number of our colleagues who provided images, background material, and suggestions. We also would like to thank RuthAnne Bump for her help with the illustrations.
Table of Contents
Front Matter
Copyright
Dedication
Preface
Acknowledgments
Chapter 1: Radioactivity, Radionuclides, and Radiopharmaceuticals
Chapter 2: Instrumentation and Quality Control
Chapter 3: Central Nervous System
Chapter 4: Thyroid, Parathyroid, and Salivary Glands
Chapter 5: Cardiovascular System
Chapter 6: Respiratory System
Chapter 7: Gastrointestinal Tract
Chapter 8: Skeletal System
Chapter 9: Genitourinary System and Adrenal Glands
Chapter 10: Non-PET Neoplasm Imaging and Radioimmunotherapy
Chapter 11: 18 F-FDG PET/CT Neoplasm Imaging
Chapter 12: Inflammation and Infection Imaging
Chapter 13: Authorized User and Radioisotope Safety Issues
Unknown Case Sets
Answers to Unknown Case Sets
Characteristics of Radionuclides for Imaging and Therapy
Radioactivity Conversion Table for International System (SI) Units (Becquerels to Curies)
Radioactivity Conversion Table for International System (SI) Units (Curies to Becquerels)
Technetium-99m Decay and Generation Tables
Other Radionuclide Decay Tables
Injection Techniques and Pediatric Dosages
Sample Techniques for Nuclear Imaging
Abnormal Radiopharmaceutical Distribution as a Result of Medications and Other Extrinsic Factors
Nonradioactive Pharmaceuticals in Nuclear Medicine
Pregnancy and Breastfeeding
General Considerations for Hospitalized Patients Receiving Radionuclide Therapy
Special Considerations and Requirements for Iodine-131 Therapy
Emergency Procedures for Spills of Radioactive Materials
Index
1 Radioactivity, Radionuclides, and Radiopharmaceuticals

BASIC ISOTOPE NOTATION
Nuclear Stability and Decay
RADIONUCLIDE PRODUCTION
RADIOACTIVE DECAY
RADIONUCLIDE GENERATOR SYSTEMS
RADIONUCLIDES AND RADIOPHARMACEUTICALS FOR IMAGING
Technetium-99m
Iodine-123 and -131
Xenon-133
Gallium-67
Indium-111
Thallium-201
Fluorine-18 and Other Positron Emitters
Monoclonal Antibodies
Investigational Radiopharmaceuticals
RADIOPHARMACY QUALITY CONTROL
Generator and Radionuclide Purity
Radiochemical Labeling
UNSEALED RADIONUCLIDES USED FOR THERAPY
Phosphorus-32, Yttrium-90, and Gold-198
Iodine-131
Strontium-89, Samarium-153, and Rhenium-186

Basic Isotope Notation
The atom may be thought of as a collection of protons, neutrons, and electrons. The protons and neutrons are found in the nucleus, and shells of electrons orbit the nucleus with discrete energy levels. The number of neutrons is usually designated by N. The number of protons is represented by Z (also called the atomic number ). The atomic mass number, or the total number of nuclear particles, is represented by A and is simply the sum of N and Z. The symbolism used to designate atoms of a certain element hav